Cellosaurus A-673 clone Asp114 (CVCL_JM58)
Cell line name | A-673 clone Asp114 |
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Synonyms | A673 clone Asp114; ASP114; Asp114; A673/TR/shEF |
Accession | CVCL_JM58 |
Resource Identification Initiative | To cite this cell line use: A-673 clone Asp114 (RRID:CVCL_JM58) |
Comments | Problematic cell line: Misclassified. Parent cell line (A-673) was originally thought to be a rhabdomyosarcoma cell line but is an Ewing sarcoma cell line. Population: Caucasian. Characteristics: Transfected with a construct harboring a doxycycline-inducible shRNA against the EWSR1-FLI1 fusion protein. Knockout cell: Method=shRNA knockdown; HGNC; 3508; EWSR1 (Note=EWSR1-FLI1 fusion). Knockout cell: Method=shRNA knockdown; HGNC; 3749; FLI1 (Note=EWSR1-FLI1 fusion). Omics: Deep proteome analysis. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Muscle; UBERON=UBERON_0001630. |
Sequence variations |
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Disease | Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0080 (A-673) |
Sex of cell | Female |
Age at sampling | 15Y |
Category | Cancer cell line |
Publications | PubMed=17438102; DOI=10.1158/1078-0432.CCR-06-1762 PubMed=23940108; DOI=10.1101/gr.151340.112; PMCID=PMC3814880 PubMed=28062706; DOI=10.1158/1535-7163.MCT-16-0235 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_JM58 |
Encyclopedic resources | Wikidata; Q54606058 |
Gene expression databases | GEO; GSE27524 |
Proteomic databases | PRIDE; PXD002765 |
Entry history | |
Entry creation | 22-Aug-2017 |
Last entry update | 10-Sep-2024 |
Version number | 17 |