Cellosaurus HeLa-X4 (CVCL_JL48)
| Cell line name | HeLa-X4 |
|---|---|
| Synonyms | HeLa-X4-6 |
| Accession | CVCL_JL48 |
| Resource Identification Initiative | To cite this cell line use: HeLa-X4 (RRID:CVCL_JL48) |
| Comments | Population: African American. Characteristics: Engineered to express the gp160 envelope protein (Env) from a CXCR4-tropic HIV-1 isolate. Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16. Genetic integration: Method=Transfection/transduction; Gene=HIV-1 isolate NL4-3 env. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04610; HIV-1 isolate BRU/LAI tat. Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_IY74 (HeLa Tet-On) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=16314403; DOI=10.1177/1087057105282959 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54882735 |
| Entry history | |
| Entry creation | 15-May-2017 |
| Last entry update | 10-Sep-2024 |
| Version number | 11 |