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Cellosaurus AT-1 [Mouse cardiomyocyte] (CVCL_JK52)

[Text version]
Cell line name AT-1 [Mouse cardiomyocyte]
Accession CVCL_JK52
Resource Identification Initiative To cite this cell line use: AT-1 [Mouse cardiomyocyte] (RRID:CVCL_JK52)
Comments Characteristics: From transgenic mice expressing a fusion gene comprised of the atrial natriuretic factor (ANF) promoter and the SV40 early region.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Heart, left atrium; UBERON=UBERON_0002079.
Cell type: Cardiomyocyte; CL=CL_0002495.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3HeB/FeJ transgenic.
Originate from same individual CVCL_0303 ! HL-1
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1954678; DOI=10.1161/01.RES.69.6.1591
Delcarpio J.B., Lanson N.A. Jr., Field L.J., Claycomb W.C.
Morphological characterization of cardiomyocytes isolated from a transplantable cardiac tumor derived from transgenic mouse atria (AT-1 cells).
Circ. Res. 69:1591-1600(1991)

PubMed=10908350; DOI=10.1093/nar/28.15.2882; PMCID=PMC102680
Lanson N.A. Jr., Egeland D.B., Royals B.A., Claycomb W.C.
The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes.
Nucleic Acids Res. 28:2882-2892(2000)

Cross-references
Encyclopedic resources Wikidata; Q54750822
Entry history
Entry creation15-May-2017
Last entry update10-Sep-2024
Version number10