Cellosaurus cell line KH-AML-B2 (CVCL

Cross-references
Cell line name	KH-AML-B2
Accession	CVCL_JK50
Resource Identification Initiative	To cite this cell line use: KH-AML-B2 (RRID:CVCL_JK50)
Comments	Population: Japanese. Characteristics: CSF2 dependent. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys2729Asn (c.8187G>T) (8415G>T); ClinVar=VCV000038142; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser2835Ter (c.8504C>G) (8732C>A); ClinVar=VCV000267091; Zygosity=Heterozygous; Note=Mutated. This cell line contains both the mutated allele and the reverted allele (from parent cell line). Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser2835Glu (c.8503_8504TC>GA) (8731TC>GA); Zygosity=Heterozygous; Note=Reverted. This cell line contains both the mutated allele and the reverted allele (from parent cell line).
Disease	Childhood acute myeloid leukemia (NCIt: C9160) Fanconi anemia (NCIt: C62505) Acute myeloid leukemia (ORDO: Orphanet_519) Fanconi anemia (ORDO: Orphanet_84)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_JH26 (FA-AML1A)
Sex of cell	Male
Age at sampling	4Y
Category	Cancer cell line
Cell line collections (Providers)	JCRB; KURB2759
Cell line databases/resources	cancercelllines; CVCL_JK50
Encyclopedic resources	Wikidata; Q54899858
Entry history
Entry creation	15-May-2017
Last entry update	19-Dec-2024
Version number	10