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Cellosaurus TH::GFP;PrP::hSNCAA53T (CVCL_JJ82)

[Text version]
Cell line name TH::GFP;PrP::hSNCAA53T
Accession CVCL_JJ82
Resource Identification Initiative To cite this cell line use: TH::GFP;PrP::hSNCAA53T (RRID:CVCL_JJ82)
Comments Characteristics: Expresses GFP under the control of the rat TH promoter and human mutant SNCA p.Ala53Thr under the control of the mouse prion (PrP) promoter.
Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:11138; SNCA (Note=With p.Ala53Thr).
Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Breed/subspecies: C57BL/6 x B6;C3-Tg(Prnp-SNCA*A53T)83Vle/J transgenic.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=28413000; DOI=10.1016/j.scr.2016.12.026; PMCID=PMC5626016
Chumarina M., Azevedo C., Bigarreau J., Vignon C., Kim K.-S., Li J.-Y., Roybon L.
Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease.
Stem Cell Res. 19:17-20(2017)

Cross-references
Encyclopedic resources Wikidata; Q54972282
Entry history
Entry creation15-May-2017
Last entry update19-Dec-2024
Version number9