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Cellosaurus HSC-3/CMV-Luc (CVCL_JF94)

[Text version]
Cell line name HSC-3/CMV-Luc
Synonyms HSC-3 CMV-Luc
Accession CVCL_JF94
Resource Identification Initiative To cite this cell line use: HSC-3/CMV-Luc (RRID:CVCL_JF94)
Comments Population: Japanese.
Characteristics: Expression of luciferase is under the control of the CMV promoter.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1288 (HSC-3)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1685

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,13
D7S82013
D13S31712
D16S5399
TH016,9.3
TPOX8
vWA14,17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1685
JCRB; NIHS1045 - Discontinued
Encyclopedic resources Wikidata; Q54896387
Entry history
Entry creation15-May-2017
Last entry update10-Sep-2024
Version number12