ID   Sf-RVN
AC   CVCL_JF76
SY   Spodoptera frugiperda-RhabdoVirus Negative
DR   Wikidata; Q54952878
RX   Patent=WO2017075627A1;
RX   PubMed=26923062;
RX   PubMed=29133148;
RX   PubMed=34838817;
WW   https://www.sigmaaldrich.com/catalog/product/sial/sfrvn
WW   http://www.glycobac.com/sf-rvn-cells
CC   Group: Insect cell line.
CC   Group: Patented cell line.
CC   Group: Recombinant protein production insect cell line.
CC   Virology: Devoid of SfRV rhabdovirus.
CC   Doubling time: ~20 hours (PubMed=26923062).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
OX   NCBI_TaxID=7108; ! Spodoptera frugiperda (Fall armyworm)
HI   CVCL_0549 ! Sf9
SX   Female
AG   Pupal stage
CA   Spontaneously immortalized cell line
DT   Created: 15-05-17; Last updated: 29-06-23; Version: 11
//
RX   Patent=WO2017075627A1;
RA   Maghodia A.B., Geisler C., Jarvis D.L.;
RT   "Virus-free cell lines and methods for obtaining same.";
RL   Patent number WO2017075627A1, 04-May-2017.
//
RX   PubMed=26923062; DOI=10.1016/j.pep.2016.02.014;
RA   Maghodia A.B., Geisler C., Jarvis D.L.;
RT   "Characterization of an Sf-rhabdovirus-negative Spodoptera frugiperda
RT   cell line as an alternative host for recombinant protein production in
RT   the baculovirus-insect cell system.";
RL   Protein Expr. Purif. 122:45-55(2016).
//
RX   PubMed=29133148; DOI=10.1016/j.pep.2017.11.002;
RA   Geisler C., Jarvis D.L.;
RT   "Adventitious viruses in insect cell lines used for recombinant
RT   protein expression.";
RL   Protein Expr. Purif. 144:25-32(2017).
//
RX   PubMed=34838817; DOI=10.1016/j.jbc.2021.101454;
RA   Mabashi-Asazuma H., Jarvis D.L.;
RT   "A new insect cell line engineered to produce recombinant
RT   glycoproteins with cleavable N-glycans.";
RL   J. Biol. Chem. 298:101454.1-101454.13(2022).
//