Cellosaurus cell line UT-SCC-107 (CVCL

Cellosaurus UT-SCC-107 (CVCL_JA25)

Cross-references
Cell line name	UT-SCC-107
Synonyms	University of Turku-Squamous Cell Carcinoma-107
Accession	CVCL_JA25
Resource Identification Initiative	To cite this cell line use: UT-SCC-107 (RRID:CVCL_JA25)
Comments	Omics: Array-based CGH. Omics: miRNA expression profiling. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Homozygous (PubMed=29970484).
Disease	Laryngeal squamous cell carcinoma (NCIt: C4044) Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	46Y
Category	Cancer cell line
Publications	PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263 Janiszewska J., Szaumkessel M., Kostrzewska-Poczekaj M., Bednarek K., Paczkowska J., Jackowska J., Grenman R., Szyfter K., Wierzbicka M., Giefing M., Jarmuz-Szymczak M. Global miRNA expression profiling identifies miR-1290 as novel potential oncomiR in laryngeal carcinoma. PLoS ONE 10:E0144924-E0144924(2015) PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733 Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O. Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy. Mol. Cancer Ther. 17:2060-2071(2018)
Cell line databases/resources	cancercelllines; CVCL_JA25
Encyclopedic resources	Wikidata; Q54992054
Gene expression databases	GEO; GSM2883393 GEO; GSM2888856
Entry history
Entry creation	15-May-2017
Last entry update	19-Dec-2024
Version number	8