Cellosaurus cell line C3.6 (CVCL

Cellosaurus C3.6 (CVCL_J983)

Cross-references
Cell line name	C3.6
Synonyms	HB4a-C3.6
Accession	CVCL_J983
Resource Identification Initiative	To cite this cell line use: C3.6 (RRID:CVCL_J983)
Comments	Characteristics: Moderate expression of ERBB2 (PubMed=9935193). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3430; ERBB2. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58+U19). Omics: Deep proteome analysis. Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367. Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_J982 (HB4a)
Sex of cell	Female
Age at sampling	18Y
Category	Conditionally immortalized cell line
Publications	PubMed=9935193; DOI=10.1002/(SICI)1097-0215(19990129)80:3<477::AID-IJC23>3.0.CO;2-W Harris R.A., Eichholtz T.J., Hiles I.D., Page M.J., O'Hare M.J. New model of ErbB-2 over-expression in human mammary luminal epithelial cells. Int. J. Cancer 80:477-484(1999) PubMed=16685446; DOI=10.3892/ijo.28.6.1441 dos Santos M.L., Palanch C.G., Salaorni S., da Silva W.A. Jr., Nagai M.A. Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression. Int. J. Oncol. 28:1441-1461(2006)
Encyclopedic resources	Wikidata; Q54808132
Proteomic databases	PRIDE; PXD004195
Entry history
Entry creation	11-Feb-2013
Last entry update	19-Dec-2024
Version number	14