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Cellosaurus 7E3 (CVCL_J935)

[Text version]
Cell line name 7E3
Accession CVCL_J935
Resource Identification Initiative To cite this cell line use: 7E3 (RRID:CVCL_J935)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-8832.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the chimeric abciximab (ReoPro) therapeutic antibody which is used as a platelet aggregation inhibitor.
Monoclonal antibody isotype: IgG1.
Monoclonal antibody target: UniProtKB; P08514; Human ITGA2B/CD41.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

Patent=US5976532
Coller B.S., Knight D.M.
Method of antithrombotic therapy using anti-GPIIb/IIIa antibodies or fragments thereof, including c7E3.
Patent number US5976532, 02-Nov-1999

Cross-references
Cell line collections (Providers) ATCC; HB-8832
Cell line databases/resources CLO; CLO_0001498
Encyclopedic resources Wikidata; Q54605106
Entry history
Entry creation11-Feb-2013
Last entry update30-Jan-2024
Version number11