ID   YUSTE
AC   CVCL_J527
DR   cancercelllines; CVCL_J527
DR   Cosmic; 1548876
DR   Wikidata; Q54995822
RX   PubMed=21543894;
RX   PubMed=21569352;
RX   PubMed=22842228;
RX   PubMed=26214590;
CC   Part of: Yale University (YU) melanoma cell collection.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26214590).
CC   Omics: Deep exome analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 16
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RX   PubMed=21543894; DOI=10.4161/cc.10.11.15777;
RA   Chan E., Patel R., Nallur S., Ratner E., Bacchiocchi A., Hoyt K.,
RA   Szpakowski S., Godshalk S., Ariyan S., Sznol M., Halaban R.,
RA   Krauthammer M., Tuck D., Slack F.J., Weidhaas J.B.;
RT   "MicroRNA signatures differentiate melanoma subtypes.";
RL   Cell Cycle 10:1845-1852(2011).
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RX   PubMed=21569352; DOI=10.1186/1471-2164-12-230;
RA   Parisi F., Ariyan S., Narayan D., Bacchiocchi A., Hoyt K., Cheng E.,
RA   Xu F., Li P.-N., Halaban R., Kluger Y.;
RT   "Detecting copy number status and uncovering subclonal markers in
RT   heterogeneous tumor biopsies.";
RL   BMC Genomics 12:230.1-230.14(2011).
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RX   PubMed=22842228; DOI=10.1038/ng.2359;
RA   Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A.,
RA   McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., Ariyan S.,
RA   Narayan D., Dutton-Regester K., Capatana A., Holman E.C.,
RA   Bosenberg M.W., Sznol M., Kluger H.M., Brash D.E., Stern D.F.,
RA   Materin M.A., Lo R.S., Mane S., Ma S.-G., Kidd K.K., Hayward N.K.,
RA   Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.;
RT   "Exome sequencing identifies recurrent somatic RAC1 mutations in
RT   melanoma.";
RL   Nat. Genet. 44:1006-1014(2012).
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RX   PubMed=26214590; DOI=10.1038/ng.3361;
RA   Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N.,
RA   Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M.,
RA   Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S.,
RA   Schlessinger J., Lifton R.P., Halaban R.;
RT   "Exome sequencing identifies recurrent mutations in NF1 and RASopathy
RT   genes in sun-exposed melanomas.";
RL   Nat. Genet. 47:996-1002(2015).
//