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Cellosaurus STC-1 (CVCL_J405)

[Text version]
Cell line name STC-1
Accession CVCL_J405
Resource Identification Initiative To cite this cell line use: STC-1 (RRID:CVCL_J405)
Comments Doubling time: 54 hours (PubMed=29787051).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P68835; Murine polyomavirus (strain A2) (MPyV) small T antigen (PyST).
Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Small intestine, duodenum; UBERON=UBERON_0002114.
Disease Neuroendocrine adenoma of the mouse intestinal tract (NCIt: C22150)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J double transgenic RIP1Tag2/Rip2pyST1.
Hierarchy Children:
CVCL_J404 (STC 6-14)CVCL_C6ND (STC-1 pGIP/Neo)
Sex of cell Sex unspecified
Age at sampling 10-13W
Category Cancer cell line
Publications

PubMed=2162628; PMCID=PMC1877573
Rindi G., Grant S.G.N., Yiangou Y., Ghatei M.A., Bloom S.R., Bautch V.L., Solcia E., Polak J.M.
Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression.
Am. J. Pathol. 136:1349-1363(1990)

PubMed=1654206
Grant S.G.N., Seidman I., Hanahan D., Bautch V.L.
Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice.
Cancer Res. 51:4917-4923(1991)

PubMed=18708196; DOI=10.1016/j.jss.2008.03.055
Poncet G., Villaume K., Walter T., Pourreyron C., Theillaumas A., Lepinasse F., Hervieu V., Cordier-Bussat M., Scoazec J.-Y., Roche C.
Angiogenesis and tumor progression in neuroendocrine digestive tumors.
J. Surg. Res. 154:68-77(2009)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=29787051; DOI=10.1007/978-3-319-16104-4_19
McCarthy T., Green B.D., Calderwood D., Gillespie A.L., Cryan J.F., Giblin L.
STC-1 cells.
(In book chapter) The impact of food bioactives on health. In vitro and ex vivo models; Verhoeckx K., Cotter P., Lopez-Exposito I., Kleiveland C., Lea T., Mackie A., Requena T., Swiatecka D., Wichers H. (eds.); pp.211-220; Springer; Cham; Switzerland (2015)

PubMed=28870797; DOI=10.1016/j.peptides.2017.08.010
Gillespie A.L., Pan X.-B., Marco-Ramell A., Meharg C., Green B.D.
Detailed characterisation of STC-1 cells and the pGIP/Neo sub-clone suggests the incretin hormones are translationally regulated.
Peptides 96:20-30(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3254
Anatomy/cell type resources BTO; BTO_0003584
Encyclopedic resources Wikidata; Q54970558
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number14