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Cellosaurus FRI (CVCL_J359)

[Text version]
Cell line name FRI
Synonyms Fri; HCT-FRI; HCT FRI
Accession CVCL_J359
Resource Identification Initiative To cite this cell line use: FRI (RRID:CVCL_J359)
Comments Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained by personal communication of Lind, Guro Elisabeth.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=24042735

Markers:
AmelogeninX
CSF1PO10
D2S133818
D3S135815,17
D5S81812
D7S8209
D8S117915,16
D13S31711
D16S53912
D18S5113
D19S43312.2,14
D21S1127,29
FGA20
TH016,9.3
TPOX8,9
vWA18

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Publications

PubMed=7329817
Brattain M.G., Brattain D.E., Fine W.D., Khaled F.M., Marks M.E., Kimball P.M., Arcolano L.A., Danbury B.H.
Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts.
Oncodev. Biol. Med. 2:355-366(1981)

PubMed=3349466
Chantret I., Barbat A., Dussaulx E., Brattain M.G., Zweibaum A.
Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.
Cancer Res. 48:1936-1942(1988)

PubMed=9000147
Cottu P.-H., Muzeau F., Estreicher A., Flejou J.-F., Iggo R.D., Thomas G., Hamelin R.
Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.
Oncogene 13:2727-2730(1996)

PubMed=9000572
Hoang J.-M., Cottu P.-H., Thuille B., Salmon R.J., Thomas G., Hamelin R.
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
Cancer Res. 57:300-303(1997)

PubMed=11526487; DOI=10.1038/sj.onc.1204611
Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.-H., Hamelin R.
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.
Oncogene 20:5025-5032(2001)

PubMed=24042735; DOI=10.1038/oncsis.2013.35; PMCID=PMC3816225
Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M., Hektoen M., Lind G.E., Lothe R.A.
Epigenetic and genetic features of 24 colon cancer cell lines.
Oncogenesis 2:e71.1-e71.8(2013)

PubMed=28683746; DOI=10.1186/s12943-017-0691-y; PMCID=PMC5498998
Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J., Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E., Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.
Multi-omics of 34 colorectal cancer cell lines -- a resource for biomedical studies.
Mol. Cancer 16:116.1-116.16(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_J359
ColonAtlas; FRI
Encyclopedic resources Wikidata; Q54835164
Gene expression databases GEO; GSM2549999
Polymorphism and mutation databases Cosmic; 711269
Cosmic; 887235
IARC_TP53; 15971
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number20