ID   CCCL-2
AC   CVCL_J327
SY   C86
DR   cancercelllines; CVCL_J327
DR   Cosmic; 1479576
DR   Wikidata; Q54808783
RX   DOI=10.1007/BF02715859;
RX   PubMed=10428757;
RX   PubMed=11589301;
RX   PubMed=20570890;
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=20570890).
DI   NCIt; C2955; Colorectal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 19-12-24; Version: 14
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RX   DOI=10.1007/BF02715859;
RA   Gerdes H., Elahi A., Chen Q.-G., Jhanwar S.C.;
RT   "Characterization of newly established colorectal cancer cell lines:
RT   correlation between cytogenetic abnormalities and allelic deletions
RT   associated with multistep tumorigenesis.";
RL   J. Genet. 79:113-123(2000).
//
RX   PubMed=10428757; DOI=10.1096/fasebj.13.11.1325;
RA   Kooby D.A., Carew J.F., Halterman M.W., Mack J.E., Bertino J.R.,
RA   Blumgart L.H., Federoff H.J., Fong Y.-M.;
RT   "Oncolytic viral therapy for human colorectal cancer and liver
RT   metastases using a multi-mutated herpes simplex virus type-1 (G207).";
RL   FASEB J. 13:1325-1334(1999).
//
RX   PubMed=11589301; DOI=10.3727/096504001108747756;
RA   Longo G.S.A., Izzo J., Gorlick R., Banerjee D., Jhanwar S.C.,
RA   Bertino J.R.;
RT   "Characterization and drug sensitivity of four newly established colon
RT   adenocarcinoma cell lines to antifolate inhibitors of thymidylate
RT   synthase.";
RL   Oncol. Res. 12:309-314(2001).
//
RX   PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514;
RA   Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S.,
RA   Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C.M.,
RA   Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M.,
RA   Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.;
RT   "Genomic and biological characterization of exon 4 KRAS mutations in
RT   human cancer.";
RL   Cancer Res. 70:5901-5911(2010).
//