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Cellosaurus U-251MG-Luc (CVCL_J269)

[Text version]
Cell line name U-251MG-Luc
Synonyms U-251 MG-Luc
Accession CVCL_J269
Resource Identification Initiative To cite this cell line use: U-251MG-Luc (RRID:CVCL_J269)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1386

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,12
D7S82010,12
D13S31710,11
D16S53912
TH019.3
TPOX8
vWA16,18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1386
JCRB; NIHS0645 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J269
Encyclopedic resources Wikidata; Q54973556
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number22