Cellosaurus logo
expasy logo

Cellosaurus BT-549-Luc (CVCL_J245)

[Text version]
Cell line name BT-549-Luc
Accession CVCL_J245
Resource Identification Initiative To cite this cell line use: BT-549-Luc (RRID:CVCL_J245)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene fusion; HGNC; HGNC:2092; CLTC + HGNC; HGNC:29559; VMP1; Name(s)=CLTC-VMP1 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val275fs*1 (c.821delG) (p.W274fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_607del343; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>C); ClinVar=VCV000406598; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1092 (BT-549)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1373

Markers:
AmelogeninX
CSF1PO10,12
D5S81811
D7S8209
D13S31711
D16S5398
TH019.3
TPOX8
vWA15

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) JCRB; JCRB1373
JCRB; NIHS0637 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J245
Encyclopedic resources Wikidata; Q54798474
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number24