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Cellosaurus BT-20/CMV-Luc (CVCL_J244)

[Text version]
Cell line name BT-20/CMV-Luc
Accession CVCL_J244
Resource Identification Initiative To cite this cell line use: BT-20/CMV-Luc (RRID:CVCL_J244)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Characteristics: Expression of luciferase is under the control of the CMV promoter (JCRB=JCRB1438).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro539Arg (c.1616C>G); ClinVar=VCV000376243; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ile388Ser (c.1163T>G); ClinVar=VCV000665312; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Pro515Leu (c.1544C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0178 (BT-20)
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1438

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S82010
D13S31711
D16S53911,14
TH017,9.3
TPOX11
vWA16,17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1438
JCRB; NIHS0700 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J244
Encyclopedic resources Wikidata; Q54798451
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number24