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Cellosaurus AsPC-1/CMV-Luc (CVCL_J243)

[Text version]
Cell line name AsPC-1/CMV-Luc
Accession CVCL_J243
Resource Identification Initiative To cite this cell line use: AsPC-1/CMV-Luc (RRID:CVCL_J243)
Comments Population: Caucasian.
Characteristics: Expression of luciferase is under the control of the CMV promoter.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; 6844; MAP2K4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Leu78Hisfs*41 (c.233_234delTC) (p.His93Profs*67, c.276_277delTC); ClinVar=VCV000977782; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Arg100Thr (c.299G>C); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys135Alafs*35 (c.403delT); ClinVar=VCV001069265; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0152 (AsPC-1)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1454

Markers:
AmelogeninX
CSF1PO10,13
D5S81812
D7S82012,13
D13S3179,12
D16S53911
TH017,9.3
TPOX8,10
vWA17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1454
JCRB; NIHS0697 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J243
Encyclopedic resources Wikidata; Q54750738
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number25