Cellosaurus cell line FU-266 (CVCL

Cellosaurus FU-266 (CVCL_J235)

[Text version]

Cell line name

FU-266

Synonyms

FU 266

Accession

CVCL_J235

Resource Identification Initiative

To cite this cell line use: FU-266 (RRID:CVCL_J235)

Comments

Population: Caucasian.
Characteristics: Produces IgE lambda (from parent cell line).
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).

Disease

Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0566 (U266B1)
Children:

CVCL_J236 (FU-266 clone E1)

Sex of cell

Male

Age at sampling

53Y