ID   YUKSI
AC   CVCL_J068
DR   cancercelllines; CVCL_J068
DR   Cosmic; 1548863
DR   Cosmic; 2439333
DR   Wikidata; Q54995675
RX   PubMed=21521745;
RX   PubMed=21543894;
RX   PubMed=21569352;
RX   PubMed=23012583;
RX   PubMed=26214590;
CC   Part of: Yale University (YU) melanoma cell collection.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Unspecified (PubMed=26214590).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 16
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RX   PubMed=21521745; DOI=10.1158/1541-7786.MCR-10-0512;
RA   Tworkoski K., Singhal G., Szpakowski S., Zito C.I., Bacchiocchi A.,
RA   Muthusamy V., Bosenberg M.W., Krauthammer M., Halaban R., Stern D.F.;
RT   "Phosphoproteomic screen identifies potential therapeutic targets in
RT   melanoma.";
RL   Mol. Cancer Res. 9:801-812(2011).
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RX   PubMed=21543894; DOI=10.4161/cc.10.11.15777;
RA   Chan E., Patel R., Nallur S., Ratner E., Bacchiocchi A., Hoyt K.,
RA   Szpakowski S., Godshalk S., Ariyan S., Sznol M., Halaban R.,
RA   Krauthammer M., Tuck D., Slack F.J., Weidhaas J.B.;
RT   "MicroRNA signatures differentiate melanoma subtypes.";
RL   Cell Cycle 10:1845-1852(2011).
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RX   PubMed=21569352; DOI=10.1186/1471-2164-12-230;
RA   Parisi F., Ariyan S., Narayan D., Bacchiocchi A., Hoyt K., Cheng E.,
RA   Xu F., Li P.-N., Halaban R., Kluger Y.;
RT   "Detecting copy number status and uncovering subclonal markers in
RT   heterogeneous tumor biopsies.";
RL   BMC Genomics 12:230.1-230.14(2011).
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RX   PubMed=23012583;
RA   Parisi F., Micsinai M., Strino F., Ariyan S., Narayan D.,
RA   Bacchiocchi A., Cheng E., Xu F., Li P.-N., Kluger H.M., Halaban R.,
RA   Kluger Y.;
RT   "Integrated analysis of tumor samples sheds light on tumor
RT   heterogeneity.";
RL   Yale J. Biol. Med. 85:347-361(2012).
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RX   PubMed=26214590; DOI=10.1038/ng.3361;
RA   Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N.,
RA   Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M.,
RA   Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S.,
RA   Schlessinger J., Lifton R.P., Halaban R.;
RT   "Exome sequencing identifies recurrent mutations in NF1 and RASopathy
RT   genes in sun-exposed melanomas.";
RL   Nat. Genet. 47:996-1002(2015).
//