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Cellosaurus PC14HM (CVCL_J032)

[Text version]
Cell line name PC14HM
Accession CVCL_J032
Resource Identification Initiative To cite this cell line use: PC14HM (RRID:CVCL_J032)
Comments Problematic cell line: Contaminated. Parent cell line (PC-14) has been shown to be a PC-9 derivative.
Population: Japanese.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1640 (PC-14)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=22922681; DOI=10.3892/or.2012.1972
Nakano T., Shimizu K., Kawashima O., Kamiyoshihara M., Kakegawa S., Sugano M., Ibe T., Nagashima T., Kaira K., Sunaga N., Ohtaki Y., Atsumi J., Takeyoshi I.
Establishment of a human lung cancer cell line with high metastatic potential to multiple organs: gene expression associated with metastatic potential in human lung cancer.
Oncol. Rep. 28:1727-1735(2012)

Cross-references
Encyclopedic resources Wikidata; Q54938559
Entry history
Entry creation11-Feb-2013
Last entry update21-Mar-2023
Version number16