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Cellosaurus BJAB-K20 (CVCL_IZ94)

[Text version]
Cell line name BJAB-K20
Synonyms BJAB K20; BJA-B K20; K20
Accession CVCL_IZ94
Resource Identification Initiative To cite this cell line use: BJAB-K20 (RRID:CVCL_IZ94)
Comments Population: African; Kenyan.
Characteristics: Lacks UDP-GlcNAc 2-epimerase activity.
Virology: EBV-negative.
Omics: N-glycan profiling.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=10334995; DOI=10.1126/science.284.5418.1372
Keppler O.T., Hinderlich S., Langner J., Schwartz-Albiez R., Reutter W., Pawlita M.
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation.
Science 284:1372-1376(1999)

PubMed=10336988; DOI=10.1093/glycob/9.6.557
Keppler O.T., Peter M.E., Hinderlich S., Moldenhauer G., Stehling P., Schmitz I., Schwartz-Albiez R., Reutter W., Pawlita M.
Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus.
Glycobiology 9:557-569(1999)

PubMed=22944676; DOI=10.1515/hsz-2012-0195
Reinke S.O., Bayer M., Berger M., Hinderlich S., Blanchard V.
The analysis of N-glycans of cell membrane proteins from human hematopoietic cell lines reveals distinctions in their pattern.
Biol. Chem. 393:731-747(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IZ94
Encyclopedic resources Wikidata; Q54796991
Entry history
Entry creation15-May-2017
Last entry update02-May-2024
Version number11