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Cellosaurus P388/ADR (CVCL_IZ75)

[Text version]
Cell line name P388/ADR
Synonyms P388/Adr; P388/adr
Accession CVCL_IZ75
Resource Identification Initiative To cite this cell line use: P388/ADR (RRID:CVCL_IZ75)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_7222 (P388)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=3335022
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)

PubMed=3402281; DOI=10.1002/cyto.990090413
Ross D.D., Ordonez J.V., Joneckis C.C., Testa J.R., Thompson B.W.
Isolation of highly multidrug-resistant P388 cells from drug-sensitive P388/S cells by flow cytometric cell sorting.
Cytometry 9:359-367(1988)

PubMed=1849151; DOI=10.1172/JCI115154; PMCID=PMC295200
Gupta S., Kim J., Gollapudi S.
Reversal of daunorubicin resistance in P388/ADR cells by itraconazole.
J. Clin. Invest. 87:1467-1469(1991)

Cross-references
Cell line collections (Providers) NCI-DTP; P388/ADR
Chemistry resources ChEMBL-Cells; CHEMBL3307566
ChEMBL-Targets; CHEMBL614218
PubChem_Cell_line; CVCL_IZ75
Encyclopedic resources Wikidata; Q54937256
Entry history
Entry creation15-May-2017
Last entry update05-Oct-2023
Version number7