Cellosaurus cell line P388/ADR (CVCL

Cellosaurus P388/ADR (CVCL_IZ75)

Cross-references
Cell line name	P388/ADR
Synonyms	P388/Adr; P388/adr
Accession	CVCL_IZ75
Resource Identification Initiative	To cite this cell line use: P388/ADR (RRID:CVCL_IZ75)
Comments	Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin). Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Disease	Mouse lymphoma (NCIt: C21602)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: DBA/2.
Hierarchy	Parent: CVCL_7222 (P388)
Sex of cell	Female
Category	Cancer cell line
Publications	PubMed=3335022 Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res. 48:589-601(1988) PubMed=3402281; DOI=10.1002/cyto.990090413 Ross D.D., Ordonez J.V., Joneckis C.C., Testa J.R., Thompson B.W. Isolation of highly multidrug-resistant P388 cells from drug-sensitive P388/S cells by flow cytometric cell sorting. Cytometry 9:359-367(1988) PubMed=1849151; DOI=10.1172/JCI115154; PMCID=PMC295200 Gupta S., Kim J., Gollapudi S. Reversal of daunorubicin resistance in P388/ADR cells by itraconazole. J. Clin. Invest. 87:1467-1469(1991)
Cell line collections (Providers)	NCI-DTP; P388/ADR
Chemistry resources	ChEMBL-Cells; CHEMBL3307566 ChEMBL-Targets; CHEMBL614218 PubChem_Cell_line; CVCL_IZ75
Encyclopedic resources	Wikidata; Q54937256
Entry history
Entry creation	15-May-2017
Last entry update	19-Dec-2024
Version number	8