ID   UROtsa Cd#6
AC   CVCL_IX08
SY   UTCd#6; UROtsa_Cd_6
DR   GEO; GSM659715
DR   Wikidata; Q54991842
RX   PubMed=19921857;
RX   PubMed=30550540;
CC   Characteristics: Tumorigenic derivative of UROtsa. Subcutaneous injection of this cell line in nude mice produces tumors.
CC   Doubling time: 16.9 +- 1.0 hours (PubMed=19921857).
CC   Transformant: ChEBI; CHEBI:48775; Cadmium(2+).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Urinary bladder, urothelium; UBERON=UBERON_0004645.
CC   Cell type: Urothelial cell; CL=CL_0000731.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0571 ! UROtsa
SX   Female
AG   12Y
CA   Transformed cell line
DT   Created: 15-05-17; Last updated: 29-06-23; Version: 8
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RX   PubMed=19921857; DOI=10.1021/tx900346q;
RA   Somji S., Zhou X.-D., Mehus A., Sens M.A., Garrett S.H., Lutz K.L.,
RA   Dunlevy J.R., Zheng Y., Sens D.A.;
RT   "Variation of keratin 7 expression and other phenotypic
RT   characteristics of independent isolates of cadmium transformed human
RT   urothelial cells (UROtsa).";
RL   Chem. Res. Toxicol. 23:348-356(2010).
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RX   PubMed=30550540; DOI=10.1371/journal.pone.0207877;
RA   Hoggarth Z.E., Osowski D.B., Freeberg B.A., Garrett S.H., Sens D.A.,
RA   Sens M.A., Zhou X.-D., Zhang K.K., Somji S.;
RT   "The urothelial cell line UROtsa transformed by arsenite and cadmium
RT   display basal characteristics associated with muscle invasive
RT   urothelial cancers.";
RL   PLoS ONE 13:E0207877-E0207877(2018).
//