Cellosaurus cell line AT6ABR (CVCL

Cellosaurus AT6ABR (CVCL_IW70)

Cross-references
Cell line name	AT6ABR
Synonyms	Ataxia Telangiectasia 6 Australia BRisbane
Accession	CVCL_IW70
Resource Identification Initiative	To cite this cell line use: AT6ABR (RRID:CVCL_IW70)
Comments	From: Queensland Institute of Medical Research; Brisbane; Australia. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:795; ATM; Simple; p.Cys2824Tyr (c.8471G>A); ClinVar=VCV000234209; Zygosity=Heterozygous (PubMed=9150358).
Disease	Ataxia telangiectasia syndrome (NCIt: C2887) Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=6228733; DOI=10.1016/0167-8817(83)90030-5 Imray F.P., Kidson C. Perturbations of cell-cycle progression in gamma-irradiated ataxia telangiectasia and Huntington's disease cells detected by DNA flow cytometric analysis. Mutat. Res. 112:369-382(1983) PubMed=6504056; DOI=10.1016/0027-5107(84)90149-0 Chen P., Imray F.P., Kidson C. Gene dosage and complementation analysis of ataxia telangiectasia lymphoblastoid cell lines assayed by induced chromosome aberrations. Mutat. Res. 129:165-172(1984) PubMed=9150358; DOI=10.1038/sj.onc.1201037 Watters D., Khanna K.K., Beamish H.J., Birrell G.W., Spring K., Kedar P., Gatei M., Stenzel D., Hobson K., Kozlov S.V., Zhang N., Farrell A., Ramsay J., Gatti R.A., Lavin M.F. Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene 14:1911-1921(1997)
Encyclopedic resources	Wikidata; Q54750959
Entry history
Entry creation	03-Mar-2017
Last entry update	19-Dec-2024
Version number	11