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Cellosaurus RD/18 (CVCL_IU87)

[Text version]
Cell line name RD/18
Synonyms RD18
Accession CVCL_IU87
Resource Identification Initiative To cite this cell line use: RD/18 (RRID:CVCL_IU87)
Comments Population: Caucasian.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=1917385
Lollini P.-L., De Giovanni C., Landuzzi L., Nicoletti G., Scotlandi K., Nanni P.
Reduced metastatic ability of in vitro differentiated human rhabdomyosarcoma cells.
Invasion Metastasis 11:116-124(1991)

PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X
Scotlandi K., Serra M., Manara M.C., Benini S., Sarti M., Maurici D., Lollini P.-L., Picci P., Bertoni F., Baldini N.
Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.
Hum. Pathol. 27:408-416(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IU87
Encyclopedic resources Wikidata; Q54949541
Polymorphism and mutation databases Cosmic; 1082514
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number14