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Cellosaurus PSU-SK-1 (CVCL_IU86)

[Text version]
Cell line name PSU-SK-1
Accession CVCL_IU86
Resource Identification Initiative To cite this cell line use: PSU-SK-1 (RRID:CVCL_IU86)
Comments Senescence: Senesces at 35 PDL (PubMed=27698927).
Doubling time: 24 hours (Note=At 7th passage), 72 hours (Note=At 30th passage) (PubMed=27698927).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Pro (c.133T>C); ClinVar=VCV000017589; Zygosity=Unspecified (PubMed=27698927).
  • Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg433Ter (c.1297C>T) (R413*) (R430*); Zygosity=Unspecified (PubMed=27698927).
Disease Kidney Wilms tumor (NCIt: C40407)
Wilms tumor-aniridia-genitourinary anomalies-mental retardation syndrome (NCIt: C3718)
Nephroblastoma (ORDO: Orphanet_654)
WAGR syndrome (ORDO: Orphanet_893)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 8Y
Category Finite cell line
Publications

PubMed=27698927; DOI=10.7150/jca.16316; PMCID=PMC5039371
Theerakitthanakul K., Kruatong J., Kruatong J., Graidist P., Raungrut P., Kayasut K., Sangkhathat S.
Senescence process in primary Wilms' tumor cell culture induced by p53 independent p21 expression.
J. Cancer 7:1867-1876(2016)

Cross-references
Encyclopedic resources Wikidata; Q54948616
Polymorphism and mutation databases Cosmic; 2569715
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number14