ID   VUMC-DIPG-A
AC   CVCL_IT43
SY   VU-DIPG-A; VU-DIPG.A; DIPG-A
DR   cancercelllines; CVCL_IT43
DR   Wikidata; Q54993418
RX   PubMed=23637844;
RX   PubMed=25939062;
CC   Sequence variation: Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (PubMed=25939062).
CC   Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
DI   NCIt; C94764; Diffuse intrinsic pontine glioma
DI   ORDO; Orphanet_497188; Diffuse intrinsic pontine glioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   3Y
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 19-12-24; Version: 13
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RX   PubMed=23637844; DOI=10.1371/journal.pone.0061512; PMCID=PMC3639279;
RA   Veringa S.J.E., Biesmans D., van Vuurden D.G., Jansen M.H.A.,
RA   Wedekind L.E., Horsman I., Wesseling P., Vandertop W.P., Noske D.P.,
RA   Kaspers G.J.L., Hulleman E.;
RT   "In vitro drug response and efflux transporters associated with drug
RT   resistance in pediatric high grade glioma and diffuse intrinsic
RT   pontine glioma.";
RL   PLoS ONE 8:E61512-E61512(2013).
//
RX   PubMed=25939062; DOI=10.1038/nm.3855; PMCID=PMC4862411;
RA   Grasso C.S., Tang Y.-J., Truffaux N., Berlow N.E., Liu L.-N.,
RA   Debily M.-A., Quist M.J., Davis L.E., Huang E.C., Woo P.J.,
RA   Ponnuswami A., Chen S., Johung T.B., Sun W.-C., Kogiso M., Du Y.-C.,
RA   Qi L., Huang Y.-L., Hutt-Cabezas M., Warren K.E., Le Dret L.,
RA   Meltzer P.S., Mao H., Quezado M., van Vuurden D.G., Abraham J.,
RA   Fouladi M., Svalina M.N., Wang N., Hawkins C., Nazarian J.,
RA   Alonso M.M., Raabe E.H., Hulleman E., Spellman P.T., Li X.-N.,
RA   Keller C., Pal R., Grill J., Monje M.;
RT   "Functionally defined therapeutic targets in diffuse intrinsic pontine
RT   glioma.";
RL   Nat. Med. 21:555-559(2015).
//