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Cellosaurus U3121MG (CVCL_IS02)

[Text version]
Cell line name U3121MG
Synonyms U3121-MG; U3121
Accession CVCL_IS02
Resource Identification Initiative To cite this cell line use: U3121MG (RRID:CVCL_IS02)
Comments Part of: Human Glioblastoma Cell Culture (HGCC) resource.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Unexplicit; Ex2-5del; Zygosity=Unspecified (PubMed=27974212).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): PubMed=27974212

Markers:
AmelogeninX,Y
CSF1PO9,12
D2S133816,17
D3S135814,15
D5S8187,12
D7S82010,13
D8S117913,14
D13S31712
D16S53911,12
D18S5112,14
D19S43313,15.2
D21S1128,30
FGA19,24
TH019.3
TPOX8,9
vWA17,19

Run an STR similarity search on this cell line
Web pages http://www.hgcc.se/
Publications

PubMed=26629530; DOI=10.1016/j.ebiom.2015.08.026
Xie Y., Bergstrom T., Jiang Y.-W., Johansson P., Marinescu V.D., Lindberg N., Segerman A., Wicher G., Niklasson M., Baskaran S., Sreedharan S., Everlien I., Kastemar M., Hermansson A., Elfineh L., Libard S., Holland E.C., Hesselager G., Alafuzoff I., Westermark B., Nelander S., Forsberg-Nilsson K., Uhrbom L.
The Human Glioblastoma Cell Culture resource: validated cell models representing all molecular subtypes.
EBioMedicine 2:1351-1363(2015)

PubMed=27974212; DOI=10.1016/j.celrep.2016.11.056
Segerman A., Niklasson M., Haglund C., Bergstrom T., Jarvius M., Xie Y., Westermark A., Sonmez D., Hermansson A., Kastemar M., Naimaie-Ali Z., Nyberg F., Berglund M., Sundstrom M., Hesselager G., Uhrbom L., Gustafsson M., Larsson R., Fryknas M., Segerman B., Westermark B.
Clonal variation in drug and radiation response among glioma-initiating cells is linked to proneural-mesenchymal transition.
Cell Rep. 17:2994-3009(2016)

PubMed=28122246; DOI=10.1016/j.celrep.2017.01.003
Jiang Y.-W., Marinescu V.D., Xie Y., Jarvius M., Maturi N.P., Haglund C., Olofsson S., Lindberg N., Olofsson T., Leijonmarck C., Hesselager G., Alafuzoff I., Fryknas M., Larsson R., Nelander S., Uhrbom L.
Glioblastoma cell malignancy and drug sensitivity are affected by the cell of origin.
Cell Rep. 18:977-990(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IS02
Encyclopedic resources Wikidata; Q54973733
Gene expression databases GEO; GSM1857612
GEO; GSM1857828
GEO; GSM2368454
GEO; GSM2368585
Polymorphism and mutation databases Progenetix; CVCL_IS02
Entry history
Entry creation03-Mar-2017
Last entry update05-Oct-2023
Version number8