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Cellosaurus GT9 (CVCL_IR53)

[Text version]
Cell line name GT9
Accession CVCL_IR53
Resource Identification Initiative To cite this cell line use: GT9 (RRID:CVCL_IR53)
Comments Group: Patented cell line.
Doubling time: 36 hours (PubMed=7757303).
Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249_Pro250delinsSerAla (c.747_748delGCinsTG); Zygosity=Homozygous (PubMed=7757303).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
Publications

Patent=WO1995007105A1
Sobol R.E., Royston I., Fakhrai H.
Haplotype-matched cytokine-secreting cells and methods of using to stimulate an immune response.
Patent number WO1995007105A1, 16-Mar-1995

PubMed=7757303; DOI=10.1007/BF02639435
Gjerset R.A., Fakhrai H., Shawler D.L., Turla S., Dorigo O., Grover-Bardwick A., Mercola D., Wen S.-F., Collins H., Lin H., Varella-Garcia M., Kruse C.A., Royston I., Sobol R.E.
Characterization of a new human glioblastoma cell line that expresses mutant p53 and lacks activation of the PDGF pathway.
In Vitro Cell. Dev. Biol. Anim. 31:207-214(1995)

Cross-references
Encyclopedic resources Wikidata; Q54871833
Polymorphism and mutation databases IARC_TP53; 4530
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number10