Cellosaurus cell line PSC-THP1 (CVCL

Cellosaurus PSC-THP1 (CVCL_IR08)

[Text version]

Cell line name

PSC-THP1

Accession

CVCL_IR08

Resource Identification Initiative

To cite this cell line use: PSC-THP1 (RRID:CVCL_IR08)

Comments

Group: Patented cell line.
Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 05005.
Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).

Disease

Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0006 (THP-1)
Children:

CVCL_IR09 (PSC-THP1-chondrocyte-like)

CVCL_W367 (PSC-THP1-EP)

Sex of cell

Male

Age at sampling