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Cellosaurus CAP (CVCL_IQ88)

[Text version]
Cell line name CAP
Synonyms CEVEC's Amniocyte Production; N52.E6
Accession CVCL_IQ88
Resource Identification Initiative To cite this cell line use: CAP (RRID:CVCL_IQ88)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2416.
Characteristics: Used for stable production of recombinant proteins.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03281; Adenovirus 5 pIX.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A/E1B).
Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
Cell type: Amniocyte; CL=CL_0002323.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A8RY (CAP-CD63-tGFP)CVCL_A8SA (CAP-CD63-tGFP-Null)CVCL_A8RZ (CAP-pStbl-empty)
CVCL_WI61 (CAP-T)
Originate from same individual CVCL_IQ89 ! N52.F4
Age at sampling Fetus
Category Transformed cell line
Web pages https://cevec.com/technology/
Publications

PubMed=11044912; DOI=10.1089/104303400750001417
Schiedner G., Hertel S., Kochanek S.
Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production.
Hum. Gene Ther. 11:2105-2116(2000)

Patent=US6558948
Kochanek S., Schiedner G.
Permanent amniocytic cell line, its production and use for the production of gene transfer vectors.
Patent number US6558948, 06-May-2003

PubMed=22373410; DOI=10.1186/1753-6561-5-S8-P66; PMCID=PMC3284939
Essers R., Kewes H., Schiedner G.
Improving volumetric productivity of a stable human CAP cell line by bioprocess optimization.
BMC Proc. 5 Suppl. 8:P66-P66(2011)

PubMed=22373426; DOI=10.1186/1753-6561-5-S8-P133; PMCID=PMC3284976
Wolfel J., Essers R., Bialek C., Hertel S., Scholz-Neumann N., Schiedner G.
CAP-T cell expression system: a novel rapid and versatile human cell expression system for fast and high yield transient protein expression.
BMC Proc. 5 Suppl. 8:P133-P133(2011)

PubMed=22821436; DOI=10.1007/s00253-012-4238-2
Genzel Y., Behrendt I., Rodig J., Rapp E., Kueppers C., Kochanek S., Schiedner G., Reichl U.
CAP, a new human suspension cell line for influenza virus production.
Appl. Microbiol. Biotechnol. 97:111-122(2013)

Cross-references
Cell line databases/resources Lonza; 1310
Encyclopedic resources Wikidata; Q54907345
Entry history
Entry creation03-Mar-2017
Last entry update10-Sep-2024
Version number10