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Cellosaurus NM-D4 (CVCL_IQ44)

[Text version]
Cell line name NM-D4
Synonyms K562-D4
Accession CVCL_IQ44
Resource Identification Initiative To cite this cell line use: NM-D4 (RRID:CVCL_IQ44)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2605.
Population: Caucasian.
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

Patent=US8283161
Goletz S., Baumeister H., Schlangstedt M., Schober U.
Tumour cell lines and uses thereof.
Patent number US8283161, 09-Oct-2012

Cross-references
Encyclopedic resources Wikidata; Q54930803
Entry history
Entry creation03-Mar-2017
Last entry update02-May-2024
Version number16