ID   BT 145
AC   CVCL_IP10
SY   BT-145; BT145
DR   BTO; BTO_0005950
DR   PharmacoDB; BT145_116_2019
DR   Wikidata; Q54798421
RX   PubMed=25184684;
RX   PubMed=25366336;
RX   PubMed=27723727;
CC   Characteristics: Low-passage-number culture.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=27723727).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 19-12-24; Version: 9
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RX   PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667;
RA   Holmberg Olausson K., Maire C.L., Haidar S., Ling J., Learner E.,
RA   Nister M., Ligon K.L.;
RT   "Prominin-1 (CD133) defines both stem and non-stem cell populations in
RT   CNS development and gliomas.";
RL   PLoS ONE 9:E106694-E106694(2014).
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RX   PubMed=25366336; DOI=10.1093/neuonc/nou303; PMCID=PMC4482855;
RA   Green A.L., Ramkissoon S.H., McCauley D., Jones K., Perry J.A.,
RA   Hsu J.H.-R., Ramkissoon L.A., Maire C.L., Hubbell-Engler B., Knoff D.S.,
RA   Shacham S., Ligon K.L., Kung A.L.-J.;
RT   "Preclinical antitumor efficacy of selective exportin 1 inhibitors in
RT   glioblastoma.";
RL   Neuro-oncol. 17:697-707(2015).
//
RX   PubMed=27723727; DOI=10.1038/nbt.3697; PMCID=PMC5142231;
RA   Stevens M.M., Maire C.L., Chou N., Murakami M.A., Knoff D.S.,
RA   Kikuchi Y., Kimmerling R.J., Liu H.-Y., Haidar S., Calistri N.L.,
RA   Cermak N., Olcum S., Cordero N.A., Idbaih A., Wen P.Y.-C.,
RA   Weinstock D.M., Ligon K.L., Manalis S.R.;
RT   "Drug sensitivity of single cancer cells is predicted by changes in
RT   mass accumulation rate.";
RL   Nat. Biotechnol. 34:1161-1167(2016).
//