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Cellosaurus HLY-1 eIF4E1 (CVCL_IN94)

[Text version]
Cell line name HLY-1 eIF4E1
Accession CVCL_IN94
Resource Identification Initiative To cite this cell line use: HLY-1 eIF4E1 (RRID:CVCL_IN94)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3287; EIF4E.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Ser206Cys (c.617C>G) (p.Ser219Cys, c.656C>G) (S219C); Zygosity=Heterozygous (from parent cell line).
Disease Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H207 (HLY-1)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25403230; DOI=10.1038/ncomms6413; PMCID=PMC4238046
Landon A.L., Muniandy P.A., Shetty A.C., Lehrmann E., Volpon L., Houng S., Zhang Y.-Q., Dai B.-J., Peroutka R.J. 3rd, Mazan-Mamczarz K., Steinhardt J., Mahurkar A., Becker K.G., Borden K.L.B., Gartenhaus R.B.
MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.
Nat. Commun. 5:5413.1-5413.15(2014)

Cross-references
Encyclopedic resources Wikidata; Q54889871
Gene expression databases GEO; GSM1511349
GEO; GSM1511350
GEO; GSM1511351
GEO; GSM1511361
GEO; GSM1511362
GEO; GSM1511363
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number9