Cellosaurus cell line JME/CF 12 (CVCL

Cross-references
Cell line name	JME/CF 12
Synonyms	JME/CF12
Accession	CVCL_IN69
Resource Identification Initiative	To cite this cell line use: JME/CF 12 (RRID:CVCL_IN69)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Nose, nasal cavity, epithelium; UBERON=UBERON_0005384.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=1701980).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=1701980; DOI=10.1152/ajplung.1990.259.6.L496 Jefferson D.M., Valentich J.D., Marini F.C., Grubman S.A., Iannuzzi M.C., Dorkin H.L., Li M., Klinger K.W., Welsh M.J. Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines. Am. J. Physiol. 259:L496-L505(1990)
Encyclopedic resources	Wikidata; Q54899006
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	16