Cellosaurus cell line 6CFSMEo- (CVCL

Cellosaurus 6CFSMEo- (CVCL_IN62)

[Text version]

Cell line name

6CFSMEo-

Synonyms

6CFSMEO

Accession

CVCL_IN62

Resource Identification Initiative

To cite this cell line use: 6CFSMEo- (RRID:CVCL_IN62)

Comments

Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Lung, bronchus, submucosal gland; UBERON=UBERON_8410043.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.

Sequence variations

Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Gln2Ter (c.4C>T); ClinVar=VCV000053980; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).
Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=15463957; PubMed=16037690).

Disease

Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_VP33 ! CFSMEo-
CVCL_IN60 ! 2CFSMEo-
CVCL_IN58 ! 3ACFSMEo-

Sex of cell

Sex unspecified

Age at sampling

Age unspecified

Category

Transformed cell line

STR profile

Source(s): Millipore=SCC157

Markers:

Amelogenin	X
CSF1PO	9,12
D3S1358	15,18
D5S818	11,12
D7S820	9
D8S1179	8,13
D13S317	12
D16S539	14
D18S51	16,20
D21S11	29,30
FGA	19
Penta D	9,10
Penta E	10,11
TH01	7,9.3
TPOX	8,11
vWA	14,17

Publications

PubMed=1375758; DOI=10.1073/pnas.89.11.5171; PMCID=PMC49251
Cozens A.L., Yezzi M.J., Chin L., Simon E.M., Finkbeiner W.E., Wagner J.A., Gruenert D.C.
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 89:5171-5175(1992)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

PubMed=16037690; DOI=10.1159/000087235
da Paula A.C., Ramalho A.S., Farinha C.M., Cheung J., Maurisse R., Gruenert D.C., Ousingsawat J., Kunzelmann K., Amaral M.D.
Characterization of novel airway submucosal gland cell models for cystic fibrosis studies.
Cell. Physiol. Biochem. 15:251-262(2005)

Cross-references

Cell line collections (Providers)

Millipore; SCC157

Encyclopedic resources

Wikidata; Q54604526

Entry history

Entry creation

01-Dec-2016

Last entry update

19-Dec-2024

Version number