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Cellosaurus TR9-7 (CVCL_IM77)

[Text version]
Cell line name TR9-7
Synonyms Tr9-7
Accession CVCL_IM77
Resource Identification Initiative To cite this cell line use: TR9-7 (RRID:CVCL_IM77)
Comments Characteristics: Expresses wild-type TP53 under the control of a tetracycline-regulated promoter.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Transcriptome analysis by microarray.
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E212 (MDAH041)
Sex of cell Female
Age at sampling 22Y
Category Cancer cell line
Publications

PubMed=7667317; DOI=10.1073/pnas.92.18.8493; PMCID=PMC41183
Agarwal M.L., Agarwal A., Taylor W.R., Stark G.R.
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.
Proc. Natl. Acad. Sci. U.S.A. 92:8493-8497(1995)

PubMed=16966095; DOI=10.1289/ehp.8969; PMCID=PMC1570045
McNeely S.C., Xu X.-G., Taylor B.F., Zacharias W., McCabe M.J. Jr., States J.C.
Exit from arsenite-induced mitotic arrest is p53 dependent.
Environ. Health Perspect. 114:1401-1406(2006)

Cross-references
Encyclopedic resources Wikidata; Q54972936
Gene expression databases GEO; GSE7101
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number9