ID   HL-60/R3
AC   CVCL_II78
DR   cancercelllines; CVCL_II78
DR   Wikidata; Q54889807
RX   PubMed=1737356;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0002 ! HL-60
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 05-10-23; Version: 16
//
RX   PubMed=1737356;
RA   Leung M.-F., Sokoloski J.A., Sartorelli A.C.;
RT   "Changes in microtubules, microtubule-associated proteins, and
RT   intermediate filaments during the differentiation of HL-60 leukemia
RT   cells.";
RL   Cancer Res. 52:949-954(1992).
//