Cellosaurus cell line UM-SCV-5 (CVCL

Cellosaurus UM-SCV-5 (CVCL_HX24)

Cross-references
Cell line name	UM-SCV-5
Synonyms	UMSCV-5; University of Michigan-Squamous cell Carcinoma of the Vulva-5
Accession	CVCL_HX24
Resource Identification Initiative	To cite this cell line use: UM-SCV-5 (RRID:CVCL_HX24)
Comments	Derived from site: In situ; Vulva; UBERON=UBERON_0000997.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr155Ile (c.464C>T); ClinVar=VCV001005876; Zygosity=Unspecified (PubMed=7503188).
Disease	Vulvar squamous cell carcinoma (NCIt: C4052) Vulvar squamous cell carcinoma (ORDO: Orphanet_494448)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	60Y
Category	Cancer cell line
Publications	PubMed=1777413; DOI=10.1002/gcc.2870030604 Worsham M.J., Van Dyke D.L., Grenman S.E., Grenman R., Hopkins M.P., Roberts J.A., Gasser K.M., Schwartz D.R., Carey T.E. Consistent chromosome abnormalities in squamous cell carcinoma of the vulva. Genes Chromosomes Cancer 3:420-432(1991) PubMed=7503188; DOI=10.1016/0002-9378(95)90636-3 Hietanen S.H., Kurvinen K., Syrjanen K.J., Grenman S.E., Carey T.E., McClatchey K.D., Syrjanen S.M. Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells. Am. J. Obstet. Gynecol. 173:1477-1482(1995) PubMed=7599042; DOI=10.1038/bjc.1995.289; PMCID=PMC2034151 Hietanen S.H., Grenman S.E., Syrjanen K.J., Lappalainen K., Kauppinen J., Carey T.E., Syrjanen S.M. Human papillomavirus in vulvar and vaginal carcinoma cell lines. Br. J. Cancer 72:134-139(1995)
Cell line databases/resources	cancercelllines; CVCL_HX24
Encyclopedic resources	Wikidata; Q54990965
Polymorphism and mutation databases	IARC_TP53; 6930
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	12