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Cellosaurus XG-3E (CVCL_HX21)

[Text version]
Cell line name XG-3E
Synonyms XG3E
Accession CVCL_HX21
Resource Identification Initiative To cite this cell line use: XG-3E (RRID:CVCL_HX21)
Comments Characteristics: Produces Ig lambda.
Characteristics: IL6 dependent.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (from autologous cell line XG-3).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4799 ! XG-3
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8204890; DOI=10.1182/blood.V83.12.3654.3654
Zhang X.-G., Gaillard J.-P., Robillard N., Lu Z.-Y., Gu Z.-J., Jourdan M., Boiron J.-M., Bataille F.-R., Klein B.
Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma.
Blood 83:3654-3663(1994)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HX21
Encyclopedic resources Wikidata; Q54994711
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number13