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Cellosaurus XR-V9B (CVCL_HM60)

[Text version]
Cell line name XR-V9B
Accession CVCL_HM60
Resource Identification Initiative To cite this cell line use: XR-V9B (RRID:CVCL_HM60)
Comments Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; Q60449; Xrcc5; Simple; p.Ile267_Gln350del84 (c.799_1050del252); Zygosity=Unspecified (PubMed=8657125).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_6296 (V79B)
Children:
CVCL_8651 (XR-V9B-4)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1438689; DOI=10.2307/3578421
Zdzienicka M.Z., van Wessel N., van der Schans G.P.
A fourth complementation group among ionizing radiation-sensitive Chinese hamster cell mutants defective in DNA double-strand break repair.
Radiat. Res. 131:309-314(1992)

PubMed=8657125; DOI=10.1128/mcb.16.4.1519; PMCID=PMC231136
Errami A., Smider V.V., Rathmell W.K., He D.-M., Hendrickson E.A., Zdzienicka M.Z., Chu G.
Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants.
Mol. Cell. Biol. 16:1519-1526(1996)

Cross-references
Encyclopedic resources Wikidata; Q54995046
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number11