Cellosaurus logo
expasy logo

Cellosaurus T47D-ST3-STn (CVCL_HG17)

[Text version]
Cell line name T47D-ST3-STn
Accession CVCL_HG17
Resource Identification Initiative To cite this cell line use: T47D-ST3-STn (RRID:CVCL_HG17)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 10862; ST3GAL1.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 23614; ST6GALNAC1.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_HG15 (T47D-ST3)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=16319059; DOI=10.1074/jbc.M511826200
Sewell R., Backstrom M., Dalziel M., Gschmeissner S., Karlsson H., Noll T., Gatgens J., Clausen H., Hansson G.C., Burchell J.M., Taylor-Papadimitriou J.
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.
J. Biol. Chem. 281:3586-3594(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_HG17
Encyclopedic resources Wikidata; Q54971566
Entry history
Entry creation01-Dec-2016
Last entry update10-Sep-2024
Version number12