ID   KK-p
AC   CVCL_HF90
SY   KKp
DR   Wikidata; Q54899971
RX   CelloPub=CLPUB00362;
RX   PubMed=12738951;
RX   PubMed=16127291;
CC   Population: Japanese.
CC   Virology: HPV16 in only detected in early passages.
CC   Doubling time: 14-48 hours (CelloPub=CLPUB00362).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_HF89 ! KK-m
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 10-09-24; Version: 13
//
RX   CelloPub=CLPUB00362;
RA   Nobumori T.;
RT   "Biological characteristics of two new cell strains isolated from a
RT   primary squamous cell carcinoma of the tongue and a nodal
RT   metastasis.";
RL   Hiroshima Daigaku Shigaku Zasshi 35:18-32(2003).
//
RX   PubMed=12738951; DOI=10.1067/moe.2003.36;
RA   Sugiyama M., Bhawal U.K., Dohmen T., Ono S., Miyauchi M., Ishikawa T.;
RT   "Detection of human papillomavirus-16 and HPV-18 DNA in normal,
RT   dysplastic, and malignant oral epithelium.";
RL   Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 95:594-600(2003).
//
RX   PubMed=16127291; DOI=10.1159/000087910;
RA   Bhawal U.K., Ozaki Y., Nishimura M., Sugiyama M., Sasahira T.,
RA   Nomura Y., Sato F., Fujimoto K., Sasaki N., Ikeda M.-a., Tsuji K.,
RA   Kuniyasu H., Kato Y.;
RT   "Association of expression of receptor for advanced glycation end
RT   products and invasive activity of oral squamous cell carcinoma.";
RL   Oncology 69:246-255(2005).
//