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Cellosaurus HeLa/PTX (CVCL_HF87)

[Text version]
Cell line name HeLa/PTX
Accession CVCL_HF87
Resource Identification Initiative To cite this cell line use: HeLa/PTX (RRID:CVCL_HF87)
Comments Population: African American.
Doubling time: 32.5 +- 2.21 hours (PubMed=25015454).
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=25015454
Bi W.-X., Wang Y.-X., Sun G.-Y., Zhang X.-J., Wei Y.-Q., Li L., Wang X.-Y.
Paclitaxel-resistant HeLa cells have up-regulated levels of reactive oxygen species and increased expression of taxol resistance gene 1.
Pak. J. Pharm. Sci. 27:871-878(2014)

Cross-references
Encyclopedic resources Wikidata; Q54882700
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number8