Cellosaurus logo
expasy logo

Cellosaurus DLD-1 BBC3(-/-) (CVCL_HD55)

[Text version]
Cell line name DLD-1 BBC3(-/-)
Synonyms BBC3 (-/-) DLD-1; DLD-1 PUMA-/-
Accession CVCL_HD55
Resource Identification Initiative To cite this cell line use: DLD-1 BBC3(-/-) (RRID:CVCL_HD55)
Comments Population: Caucasian.
Knockout cell: Method=Homologous recombination; HGNC; HGNC:17868; BBC3.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0248 (DLD-1)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=12574499; DOI=10.1073/pnas.2627984100; PMCID=PMC149936
Yu J., Wang Z., Kinzler K.W., Vogelstein B., Zhang L.
PUMA mediates the apoptotic response to p53 in colorectal cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 100:1931-1936(2003)

Cross-references
Cell line collections (Providers) Horizon_Discovery; HD+R00-029
Encyclopedic resources Wikidata; Q54831152
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number7