Cellosaurus cell line DLD-1 AKT2(-/-) (CVCL

Cross-references
Cell line name	DLD-1 AKT2(-/-)
Synonyms	AKT2 (-/-) DLD-1
Accession	CVCL_HD53
Resource Identification Initiative	To cite this cell line use: DLD-1 AKT2(-/-) (RRID:CVCL_HD53)
Comments	Population: Caucasian. Knockout cell: Method=Homologous recombination; HGNC; 392; AKT2. Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108.
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0248 (DLD-1)
Sex of cell	Male
Age at sampling	67Y
Category	Cancer cell line
Publications	PubMed=20133737; DOI=10.1073/pnas.0914018107; PMCID=PMC2823889 Ericson K., Gan C., Cheong I., Rago C., Samuels Y., Velculescu V.E., Kinzler K.W., Huso D.L., Vogelstein B., Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Proc. Natl. Acad. Sci. U.S.A. 107:2598-2603(2010) PubMed=27878243; DOI=10.3892/ijo.2016.3771; PMCID=PMC5182003 Haggblad Sahlberg S., Mortensen A.C., Haglof J., Engskog M.K.R., Arvidsson T., Pettersson C., Glimelius B., Stenerlow B., Nestor M. Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells. Int. J. Oncol. 50:5-14(2017)
Cell line collections (Providers)	Horizon_Discovery; HD+R00-002
Encyclopedic resources	Wikidata; Q54831150
Entry history
Entry creation	01-Dec-2016
Last entry update	02-May-2024
Version number	6