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Cellosaurus OP-9S (CVCL_HC57)

[Text version]
Cell line name OP-9S
Accession CVCL_HC57
Resource Identification Initiative To cite this cell line use: OP-9S (RRID:CVCL_HC57)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-10785.
Characteristics: Slow-growing derivative of OP9.
Characteristics: Does not produce Csf1 (M-CSF) due to a mutation in the gene.
Doubling time: 58-72 hours (PubMed=15650053).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6 x C3H) F2-op/op.
Hierarchy Parent: CVCL_4398 (OP9)
Children:
CVCL_HC58 (OP-9S/LMJSN)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Stromal cell line
Publications

PubMed=15650053; DOI=10.1182/blood-2004-11-4237
DeHart S.L., Heikens M.J., Tsai S.
Jagged2 promotes the development of natural killer cells and the establishment of functional natural killer cell lines.
Blood 105:3521-3527(2005)

Patent=US9121008
Tsai S.
Development of natural killer cells and functional natural killer cell lines.
Patent number US9121008, 01-Sep-2015

Cross-references
Encyclopedic resources Wikidata; Q54936438
Entry history
Entry creation01-Dec-2016
Last entry update29-Jun-2023
Version number9