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Cellosaurus ZP150 (CVCL_HB20)

[Text version]
Cell line name ZP150
Accession CVCL_HB20
Resource Identification Initiative To cite this cell line use: ZP150 (RRID:CVCL_HB20)
Comments Characteristics: Selected using the 9-(1'-pyrene)nonanol/ultraviolet (P9OH/UV) method. P9OH acts as a photosensitizer. Normal cells which can incorporate the fluorescent fatty alcohol into lipids are killed by UV, but mutants who incorporate P9OH poorly are less susceptible to photosensitized killing.
Genetic integration: Method=Transfection/transduction; Gene=RGD; 61814; Pex2.
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; Q9QYL1; Pex13; Simple; p.Asp265_Lys306del (c.793_918del126); Zygosity=Heterozygous (PubMed=10441330).
  • Mutation; UniProtKB; Q9QYL1; Pex13; Simple; p.Ser319Asn (c.956G>A); Zygosity=Heterozygous (PubMed=10441330).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_HB34 (CHOTKa)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=10441330; DOI=10.1093/hmg/8.9.1673
Toyama R., Mukai S., Itagaki A., Tamura S., Shimozawa N., Suzuki Y., Kondo N., Wanders R.J.A., Fujiki Y.
Isolation, characterization and mutation analysis of PEX13-defective Chinese hamster ovary cell mutants.
Hum. Mol. Genet. 8:1673-1681(1999)

Cross-references
Encyclopedic resources Wikidata; Q54996026
Entry history
Entry creation01-Dec-2016
Last entry update10-Sep-2024
Version number13