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Cellosaurus BER-40 (CVCL_HA73)

[Text version]
Cell line name BER-40
Synonyms BER40
Accession CVCL_HA73
Resource Identification Initiative To cite this cell line use: BER-40 (RRID:CVCL_HA73)
Comments Group: Non-human primate cell line.
Selected for resistance to: ChEBI; CHEBI:48080; Brefeldin A (BFA).
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Sequence variations
  • Mutation; UniProtKB; A0A0D9QZH2; GBF1; Simple; p.Ala796Glu (c.2387C>A) (A795E); Zygosity=Heterozygous; Note=Responsible for BFA resistance (PubMed=19023417).
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1459197; DOI=10.1016/0014-4827(92)90005-S
Chen C.-H., Kuwazuru Y., Yoshida T., Nambiar M., Wu H.C.
Isolation and characterization of a brefeldin A-resistant mutant of monkey kidney Vero cells.
Exp. Cell Res. 203:321-328(1992)

PubMed=12204114; DOI=10.1093/oxfordjournals.jbchem.a003241
Tamura T., Oda T., Muramatsu T.
Resistance against ricin-induced apoptosis in a brefeldin A-resistant mutant cell line (BER-40) of Vero cells.
J. Biochem. 132:441-449(2002)

PubMed=19023417; DOI=10.1371/journal.ppat.1000216
Belov G.A., Feng Q., Nikovics K., Jackson C.L., Ehrenfeld E.
A critical role of a cellular membrane traffic protein in poliovirus RNA replication.
PLoS Pathog. 4:E1000216-E1000216(2008)

Cross-references
Encyclopedic resources Wikidata; Q54796062
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number11